HArmonyCa Filler

What is HArmonyCa?

HArmonyCa is a hybrid injectable combining hyaluronic acid (HA) gel with calcium hydroxyapatite (CaHA) microspheres. A version containing lidocaine is available. The manufacturer describes it as a product for facial soft-tissue augmentation. The clinician must assess the specific version and its instructions for use. [1]

What effects are intended?

The HA component provides volume support, while CaHA is used for a collagen response over time. Appearance changes vary between individuals. Results equivalent to a surgical facelift or a specified degree of rejuvenation cannot be guaranteed. Manufacturer information explains the product; it does not guarantee a personal outcome. [2]

Research and duration

Clinical studies report improvements in appearance and tissue measurements. For example, one 2023 study cited by the manufacturer was non-randomised and included 15 women. Such findings do not justify promising the same amount, outcome or duration to everyone. The need for further treatment is assessed during follow-up. [3]

Suitability and treatment sites

Not every facial site is suitable for this product. Site, quantity and plan must follow its instructions. The manufacturer’s patient information lists pregnancy, breastfeeding and age under 18 among contraindications. Discuss known allergies, including lidocaine allergy, medical conditions and previous aesthetic procedures. [2]

Potential reactions and follow-up

Redness, swelling, pain, tenderness, itching and bruising may occur. Manufacturer information also includes more serious possibilities such as infection, allergy, nodules, granulomas, tissue necrosis and blindness. Sudden visual changes, severe pain or marked skin colour changes require urgent medical assessment. Aftercare and review advice should be individualised. [2]